Gluten-free • Soy-free • Lactose-free • Made in Germany
NattoZYM plus
Everything in Flux: When the Nattokinase Enzyme Meets Dandelion – for Vessels, Liver, and Urinary Tract
Per daily serving (2 capsules): 6,000 FU Nattokinase + 600 mg dandelion extract (10:1) from root & leaf
NattoZYM plus supports what should flow: Highly active nattokinase breaks down fibrin, the protein that can thicken your blood. Dandelion extract from root and leaf supports the liver, kidneys, and urinary tract in eliminating waste products. For smooth blood flow, active metabolism, and natural balance.
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Highly active nattokinase (6,000 FU) from soy-free fermentation – the enzyme supports blood flow
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Specifically cleaves fibrin: The protein responsible for blood thickening
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Dandelion extract for liver, kidneys, and urinary tract
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Gastro-resistant capsule: The enzyme specifically reaches the small intestine
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Your daily support for blood flow, liver, and metabolism – 100% vegan, soy-free, ketogenic
Gluten-free • Soy-free • Lactose-free • Made in Germany
39.00 €
1095 in stock
NattoZYM plus: Your Enzyme-Plant Complex for Blood Flow, Liver, and Natural Detoxification
Imagine your blood flowing like a clear mountain stream: free, light, unimpeded. Yet sometimes you wish for more ease. Fibrin, a fibrous protein, can thicken your blood and affect its natural flow. At the same time, your liver is working at full speed. It filters, detoxifies, and processes metabolic byproducts. But under increased strain, it may need support. And while all this is happening, your kidneys and urinary tract should eliminate what is no longer needed. Your body is a masterpiece of nature, but sometimes it lacks the right reinforcement.
This is where NattoZYM plus comes into play: An enzyme from fermented soybeans – Nattokinase – which has been consumed in Japan for centuries as Natto. This enzyme has a special ability: It specifically breaks down fibrin, the protein responsible for blood thickening. While Nattokinase dissolves the fibrin network, dandelion stands ready – that humble plant that grows in every meadow yet is so powerful. Folk medicine calls it “meadow ginseng” because it supports your liver, kidneys, and urinary tract in eliminating byproducts. The enteric-coated capsules protect the sensitive enzyme until it reaches the small intestine, where it can unfold systemically. Thus, enzyme and plant work hand in hand.
While Nattokinase with 6,000 FU (Fibrinolytic Units) enzyme activity breaks down the fibrin network in the blood and supports flow, dandelion works on three levels: The root (450 mg highly concentrated extract 10:1) supports the liver – your central filter organ. The leaf (150 mg extract 10:1) supports the kidneys and urinary tract in excretion. Together they provide 600 mg of extract, equivalent to 6 g of dried plant – or over 20 g of fresh dandelion. The result: A synergy that supports your body from blood flow to liver to excretion.
Thus, NattoZYM plus combines the power of a traditional fermentation enzyme with the wisdom of herbal medicine in a natural, vegan formula. For easy blood flow. For an active liver. For natural excretion. Made in Germany.
When NattoZYM plus is particularly useful:
- When you want to support your blood flow naturally
- When you want to support your liver in its daily filtering work
- With a protein-rich diet that requires increased metabolic work
- To support the natural excretory function via kidneys and urinary tract
- In phases of increased stress due to stress, diet, or environmental influences
- When you prefer vegan and ketogenic supplements
Why we developed NattoZYM plus:
Most products rely either on Nattokinase, without support for the liver, or on dandelion, without the enzymatic power to break down fibrin. We wanted to combine both: An enzyme that supports flow and a plant that activates the liver and excretion. The result was NattoZYM plus – for everyone who wants to support their body holistically: from blood flow to liver to natural detoxification.

Many nattokinase or dandelion products focus on high doses, but the crucial question is: Does the enzyme work alone, or does the liver receive support in elimination? The quality of an enzyme-plant complex is evident in three areas: enzyme activity, plant synergy, and intelligent protection.
What to look for when purchasing a nattokinase complex:
NattoZYM plus by dr.reinwald vital
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Conventional products
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| Enzyme activity | 6,000 FU Nattokinase per daily serving – high activity for optimal support | Often only 2,000-4,000 FU or unclear information about activity |
| Enzyme specialization | Specifically cleaves fibrin – the protein responsible for blood thickening | Often general proteases without fibrin focus |
| Plant quality | Dandelion Extract 10:1 from Root (450mg) & Leaf (150mg) = 6g Plant Dry Mass | Often lower extract ratio (e.g., 4:1) or powder instead of extract |
| Targeted Release | Gastro-resistant capsules – Enzyme is released in the small intestine for systemic effect | Often standard capsules without enteric coating – enzyme is destroyed by stomach acid |
| Synergy approach | Enzyme breaks down fibrin + dandelion supports liver & excretion – intelligent combination | Often single products (enzyme only) without plant-based co-factors |
| Purity | 100% vegan, soy-free, ketogenic, free from fillers, K1 & K2 – only 4 ingredients | Often with soy residues, K vitamins, excipients, and unnecessary additives |
How Enzyme and Plant Power Complement Each Other
Nature knows no lone fighters, and neither does your body. Enzymes break down proteins, but the resulting breakdown products need to be eliminated. Plants support the liver and excretion, but without enzymatic preparation, their task remains incomplete. NattoZYM plus follows this principle: A fermented enzyme from Japanese tradition – Nattokinase from the centuries-old Natto – combined with the “meadow ginseng” dandelion, which grows in every meadow yet is so powerful. Only through interaction does holistic support arise. For your body, which deserves complete solutions.
How the Components in NattoZYM plus Complement Each Other
NattoZYM plus is more than the sum of its parts. Each component has its own task, but only in combination do they unleash their full power. Here you can see how the synergy team works:
- Nattokinase: The Splitter
6,000 FU per daily dose
Nattokinase is your specialist for thick blood: This enzyme comes from the traditional Japanese fermentation of soybeans into Natto—a sticky, stringy food that has been consumed in Japan for over 1,000 years. What has given the Japanese vitality for centuries, you now use for your body: Nattokinase specifically splits fibrin—that fibrous protein that can thicken your blood and impede natural flow. With 6,000 FU (Fibrinolytic Units) per daily portion, NattoZYM plus provides substantial enzyme activity. Through gentle freeze-drying, the full enzyme power is preserved, while soy allergens and vitamins K1 & K2 are removed—since K vitamins promote blood clotting and would counteract the enzyme effect. But the enzyme has fulfilled its task once it has split—its plant partner takes over the support in elimination. - Dandelion from Root & Leaf: The Companion
600 mg per daily dose (450 mg root + 150 mg leaf = 6 g plant)
Here comes the companion into play: The dandelion—often cursed as a weed by farmers, revered as “meadow ginseng” by folk medicine. And that’s exactly where it comes in: While the enzyme splits fibrin, the dandelion works on three levels. The root (450 mg highly concentrated extract 10:1) supports the liver—your central filter organ that processes metabolic breakdown products every day. The leaf (150 mg extract 10:1) supports the kidneys and urinary tract in natural excretion. Together, they provide 600 mg of extract, equivalent to 6 g of dried plant—or over 20 g of fresh dandelion. Especially with enzymatic activity that breaks down proteins, nitrogen waste like ammonia is produced—and this is where the dandelion supports the liver in detoxification and elimination. Enzyme splits, dandelion accompanies—thus creating holistic support. - The Acid-Resistant Capsule Shell: The Protector
The acid-resistant HPMC capsule shell (Hydroxypropylmethylcellulose) protects the sensitive enzyme from aggressive stomach acid and releases it only in the small intestine—where it can work optimally. This way, the enzyme reaches its target unharmed and can unfold systemically in the body. The capsule is the invisible protector that ensures all others can do their work.
This is synergy: Each component makes the other stronger. Enzyme splits. Plant accompanies. Lecithin activates. Capsule protects.
Ingredients:
Dandelion root extract (Taraxaci radix), capsule shell: Hydroxypropylmethylcellulose, nattokinase, dandelion herb extract (Taraxaci herba)
Free from soy, soy allergens, genetic engineering, and vitamins K2 + K1.
Content:
60 acid-resistant capsules (28 g) – sufficient for 30 days
Nutrient Content per 2 Capsules (Daily Recommendation):
%: Nutrient Reference Value (NRV)
NRV = Nutrient Reference Value according to EU Regulation 1169/2011 | FU (Fibrinolytic Unit): indicates enzyme activity
Currently, there are no established nutrient reference values for enzymes and plant extracts.

Your Daily Enzyme Ritual for Blood Flow, Liver & Excretion:
Take a moment each day and consume 2 capsules with plenty of good water – ideally 30 minutes before a meal. This allows the enzyme to optimally prepare to reach the small intestine and unfold effectively there.
Tip: Many prefer to take NattoZYM plus in the morning on an empty stomach or before bedtime: For targeted support when the body relaxes and regenerates.
What we mean by “good water”: Pure, high-quality water such as osmosis-filtered water, fresh spring water, or still mineral water with low mineralization.
Good to know:
- Suitable for vegans
- Keto-friendly
- No known intolerances
- Soy-free: Nattokinase is free from soy allergens due to fermentation
- Free from K1 & K2: Vitamin K promotes blood clotting and has been deliberately removed
- ⚠️ May enhance the effects of blood-thinning and anticoagulant medications. If you are taking such medications, please consult your therapist beforehand.
- ⚠️ Not suitable during pregnancy and breastfeeding.
- ⚠️ Do not take before planned surgeries: You should discontinue NattoZYM plus at least 2 weeks before a surgical procedure.
Legal notice: Please adhere to the recommended daily dose. Dietary supplements are not a substitute for a balanced and varied diet and a healthy lifestyle.

Science & Studies
The fibrinolytic effect of nattokinase on the cardiovascular system has been scientifically studied for decades. The proteolytic enzyme from fermented soy is known for its ability to break down fibrin, influence blood clotting, and regulate blood pressure. Numerous clinical studies have examined its effectiveness in supporting vascular health and preventing cardiovascular risk factors. The following selection of studies provides an overview of current scientific findings:
International Studies:
- Nattokinase Supplementation and Cardiovascular Risk Factors: A Systematic Review and Meta-Analysis (Reviews in Cardiovascular Medicine, 2023)
Systematic review and meta-analysis of 6 randomized studies with 546 participants show positive effects of nattokinase on blood pressure and cardiovascular risk factors. - Nattokinase: A Promising Alternative in Prevention and Treatment of Cardiovascular Diseases (Biomedical Reports, 2018)
Comprehensive review of the fibrinolytic, antihypertensive, and anti-atherogenic properties of nattokinase with a focus on clinical relevance for cardiovascular diseases. - Effective management of atherosclerosis progress and hyperlipidemia with nattokinase (Frontiers in Cardiovascular Medicine, 2022)
Retrospective clinical study with 1,062 participants shows a 21.7% reduction in intima-media thickness and a 36% improvement in plaque formation through nattokinase supplementation. - Lipid-lowering, antihypertensive, and antithrombotic effects of nattokinase combined with red yeast rice (Frontiers in Nutrition, 2024)
Randomized double-blind study with 178 CHD patients shows significant improvements in triglycerides, cholesterol, and diastolic blood pressure through nattokinase. - Research Progress of Nattokinase in Reducing Blood Lipid (Nutrients, 2025)
Current review on lipid-lowering and anti-atherogenic mechanisms of nattokinase with a focus on activation of HSL and inhibition of HMG-CoA reductase. - Nattokinase Atherothrombotic Prevention Study – NAPS (Clinical Trials NCT02080520)
Ongoing multicenter study by the University of Southern California investigating antithrombotic and fibrinolytic effects of nattokinase on atherosclerosis progression and cognitive function. - Nattokinase Degrades SARS-CoV-2 Spike Protein In Vitro (bioRxiv, 2021)
Japanese researchers show in a preclinical laboratory study that nattokinase can degrade the spike protein of the SARS-CoV-2 virus in vitro. According to the authors, this could provide new insights into the proteolytic activity of the enzyme. Clinical data are still pending.
Study from the German-speaking Region:
- Nattokinase – An Enzyme for Blood Thinning (Zentrum der Gesundheit, 2019)
German-language overview of clinical and preclinical studies on the fibrinolytic activity of nattokinase with a focus on thrombolysis and blood pressure regulation.
Note: These studies provide indications of the fibrinolytic and cardiovascular effects of nattokinase but are not considered definitive proof. Research is an ongoing process, and further investigations will deepen the understanding of this enzyme’s mode of action. The studies mentioned are for scientific information only and do not replace medical advice. The studies cited here refer to ingredients, not the product itself.
Health-related statements according to EU Regulation 1924/2006
(approved health claims for the contained nutrients)
Currently, there are no approved health claims for nattokinase and dandelion extract under EU regulation. Both are traditionally valued and widely used in nutrition and naturopathy.
Keep out of reach of small children. Store in a cool, dry place, protected from light.
Best before: see bottom of the packaging.
Distribution: dr.reinwald vital ltd., Lord Byron Street 61–63, 5th Floor, CY-6023 Larnaca
| Content | 60 capsules (28 g) |
|---|---|
| Manufacturer | dr.reinwald vital |
| Origin | EU/Germany |
| Note | vegan |
| Ingredients | enzymes |
| Category | food supplement |
| Customs tariff number | 21069098 |
Legal Notice: This dietary supplement is intended to support nutrition. The statements refer to approved health claims. Individual results may vary. No healing or health promises are made.
Product Background
Nattokinase & Dandelion: Why the Combination of Enzyme and Plant Power is So Important for Your Well-being
Do you sometimes feel like your body needs more lightness? As if you wish for more flow? Thick blood can affect the natural flow, the liver works at full speed filtering and detoxifying, and the kidneys and urinary tract should expel what is no longer needed. What many do not know: Fibrin – a fibrous protein – can thicken your blood and impair flow. This is exactly where NattoZYM plus comes in: with the power of a fermented enzyme from Japanese tradition and a plant that has been valued as “meadow ginseng” for centuries.
The Problem: Fibrin Thickens the Blood, the Liver is Overloaded
Our modern lifestyle challenges the body: lack of exercise, carbohydrate-rich diet, stress – all of this affects our metabolism. The protein metabolism is particularly challenged. Fibrin, a fibrous protein involved in blood clotting, plays a central role in metabolic processes and affects the flow properties of the blood. At the same time, the liver works at full speed every day: it filters, metabolizes, and processes breakdown products from protein and fat metabolism – including foreign or incorrectly formed proteins. Studies show: lack of exercise, protein-rich diet, and stress can affect fibrin metabolism. Many people therefore wish for targeted support for a healthy metabolism and a well-functioning liver. The body needs specific enzymes and nutrients to physiologically break down fibrin and support liver function.
The Solution: Enzyme Power Meets Plant Tradition – Synergy Instead of Single Substance
This is where nature comes into play: Nattokinase is an enzyme derived from the traditional Japanese fermentation of soybeans into natto – that sticky, stringy food that has been consumed in Japan for over 1,000 years. What has given vitality to the Japanese for centuries, you now use for your body. Nattokinase specifically splits fibrin – that fibrous protein that can thicken your blood. But an enzyme alone is not enough: Every proteolysis (protein breakdown) produces nitrogen waste like ammonia, which challenges the liver. This is exactly where dandelion comes into play, that humble plant that grows in every meadow and is revered in folk medicine as “meadow ginseng.” The root supports the liver in detoxifying, the leaf supports the kidneys and urinary tract. Only in the interplay of enzyme and plant does holistic support arise.
What Makes NattoZYM plus Special:
- Substantial Enzyme Activity: With 6,000 FU (Fibrinolytic Units) per daily portion, NattoZYM plus is among the most active nattokinase products on the market. Many conventional products contain only 2,000-4,000 FU – NattoZYM plus provides 1.5 to 3 times more.
- Soy-Free & Vitamin K-Free: Gentle freeze-drying leaves no soy allergens. Vitamins K1 & K2 are deliberately removed, as they promote blood clotting and would counteract the enzyme effect.
- Highly Concentrated Plant Power: The dandelion extract in a 10:1 ratio from root (450 mg) and leaf (150 mg) means: 600 mg extract corresponds to 6 g of dried plant – or over 20 g of fresh dandelion. This is holistically highly concentrated plant power for liver, kidneys, and urinary tract.
- Gastric Acid-Resistant Capsules: The HPMC capsule shell protects the sensitive enzyme from aggressive stomach acid and releases it only in the small intestine – where it can become systemically active throughout the body.
- Synergy Complex According to Traditional Principle: Enzymes split fibrin, plants support liver and excretion – NattoZYM plus combines both worlds for holistic support of blood flow, liver, and natural detoxification.
- Premium Quality: 100% vegan, soy-free, ketogenic, free from fillers, maltodextrin, stearates – only 4 pure ingredients. Made in Germany.
Consumption Recommendation for Optimal Absorption
For best results, consume NattoZYM plus daily with 2 capsules and good water – preferably 30 minutes before a meal. This way, the enzyme can optimally reach the small intestine prepared and unfold systemically there. Many people particularly enjoy consuming NattoZYM plus in the morning on an empty stomach or before bedtime – for targeted support when the body comes to rest and regenerates.
NattoZYM plus combines the power of a traditional fermentation enzyme with the wisdom of herbal medicine – in a natural, vegan complex formula. For easy blood flow. For an active liver. For natural excretion.
FAQ & Frequently Asked Questions about NattoZYM plus and Nattokinase
A balanced diet is the foundation of your health—no question about it. However, fibrin, that fibrous protein that can thicken your blood, can only be influenced to a limited extent by diet alone. Nattokinase has a unique ability: it specifically breaks down fibrin and thus supports natural blood flow. Your body cannot produce this enzyme activity in sufficient amounts on its own. NattoZYM plus supplements your diet exactly where it reaches natural limits—and simultaneously provides dandelion for liver and excretion.
Because they work perfectly together: Nattokinase splits fibrin in the blood – this supports the natural flow. However, every protein breakdown (proteolysis) produces nitrogen waste like ammonia, which challenges the liver. This is where dandelion comes into play: The root supports the liver in its detoxification work, while the leaf promotes the kidneys and urinary tract in flushing out. Enzyme splits, plant aids in flushing out – this synergy makes NattoZYM plus a holistic solution.
NattoZYM plus provides 6,000 FU (Fibrinolytic Units) of nattokinase per daily serving (2 capsules). This is a substantial enzyme activity. For comparison: Many conventional products contain only 2,000–4,000 FU. Thus, NattoZYM plus delivers 1.5 to 3 times the enzyme activity – for maximum support in fibrin breakdown.
NattoZYM plus is safe when consumed as directed. The recommended daily dose of 2 capsules should not be exceeded. Important: Nattokinase has fibrinolytic (blood-thinning) properties and can enhance the effects of blood-thinning or anticoagulant medications (e.g., Marcumar, Aspirin, Heparin). If you are taking such medications, please consult your therapist beforehand. Not suitable during pregnancy and breastfeeding. Discontinue at least 2 weeks prior to planned surgeries.
NattoZYM plus is particularly beneficial for people who want to support their blood flow naturally, for those with a protein-rich diet (which requires increased liver activity), to support the natural excretory function through the kidneys and urinary tract, during phases of increased stress or lack of exercise, and for anyone who prefers vegan and ketogenic supplements.
Yes! Although nattokinase is made from fermented soybeans, the fermentation and gentle freeze-drying process eliminate any soy allergens. The finished enzyme is 100% soy-free. Additionally, vitamins K1 & K2 have been deliberately removed, as K vitamins promote blood clotting and would counteract the fibrinolytic effect. NattoZYM plus is vegan, soy-free, and ketogenic.
Consume 2 capsules daily with good water – preferably 30 minutes before a meal. This way, the enzyme can optimally prepare to reach the small intestine and unfold systemically there. Many people particularly enjoy taking NattoZYM plus in the morning on an empty stomach or before going to bed – for targeted support when the body comes to rest and regenerates.
Yes, NattoZYM plus can be well combined with other dr.reinwald vital products – especially with SerraZYM plus and SpikaZYM plus (for extended enzyme synergy) as well as with VitaDK plus (for immune system & vessels), PektiCLEAN® (for elimination of toxins) and Glutathione comp (for cell protection & metabolism).
Note: If you are taking blood-thinning medications at the same time, please consult your therapist beforehand, as nattokinase can enhance the effect.
A can contains 60 capsules and lasts for 30 days with the recommended daily dose of 2 capsules.
NattoZYM plus combines three key advantages:
- Substantial activity: 6,000 FU per daily portion (many products: only 2,000-4,000 FU).
- Synergy approach: Enzyme splits fibrin, dandelion (600 mg extract 10:1 from root & leaf = 6 g plant) supports liver and excretion.
- Premium quality: Soy-free, K1/K2-free, enteric-coated capsules for systemic effect. Additionally: 100% vegan, ketogenic, only 4 pure ingredients, Made in Germany.