Glutathion comp

What actually is glutathione?

Glutathione is currently one of the most talked about supplements and is now being traded as a kind of superfood, as it offers a large list of benefits, from detoxification, prevention of oxidative damage, to maintaining overall health and protecting the immune system. In organ tissues it is available both in its reduced form as glutathione sulph hydril (GSH) and in its oxidised form as disulphide GSSG. Glutathione is biochemically a tripeptide, an organic compound of three amino acids: cysteine, glutamic acid and glycine. For its biosynthesis in the body, however, it needs amino acids and other cofactors, such as certain B vitamins, zinc and selenium. When glutathione is mentioned as a food supplement, the reduced form GSH is usually meant.

Effects of glutathione

Glutathione is found in high concentrations in almost all mammalian tissues as well as in plants and is essential for life. It is involved in numerous biochemical processes in the organism. The compound’s mode of action has been known since the early 1920s. The best known is the body’s own elimination of harmful substances via biotransformation I and II. These are important metabolic pathways in which the dissolution and transformation of fat-bound toxins into their water-soluble, excretable substances takes place. However, glutathione also acts as a regulator of cell division, helps repair damaged DNA, increases the activity of defence cells and acts as a powerful antioxidant and scavenger of free radicals. The highest levels of glutathione are found in the liver, kidneys, pancreas and spleen, as well as in the lenses of the eyes, which are exposed to strong oxidative processes via the light of the sun.

The anti-aging industry has also long since discovered glutathione. Since its concentration in the body’s cells decreases with age, like many other substances, an increased supply of GSH is considered to have a rejuvenating effect and to refine the skin’s appearance. In addition, there is an apparent connection between the GSH levels detectable in the body and a healthy, longer life expectancy.

What happens with a glutathione deficiency?

In the case of a glutathione deficiency, chronic exhaustion (fatigue syndrome), chronic tiredness, loss of performance as well as increased susceptibility to infections occur, among other things. Oxidative stress and the depletion of the GSH pool therefore play a key role in human ageing and in almost all degenerative and chronic diseases. Since it strengthens the immune system in addition to DNA repair and cell division, it is conversely helpful in overcoming numerous diseases. ^{1 2}

Glutathion comp by dr.reinwald vital

For its biosynthesis in the body, however, it needs the aforementioned amino acids and other cofactors, such as certain B vitamins, zinc and selenium. For glutathione formation and glutathione metabolism in the body, protein intake and amino acid metabolism play a decisive role in addition to the provision of sulphur-containing substances such as thiol groups from organic sulphur. For the effective prevention of a glutathione deficiency, we therefore additionally recommend MyAMINO^® with the 8 essential amino acids as well as SulfoCLEAN^®, For the effective prevention of a glutathione deficiency, we therefore additionally recommend.

References:
¹ Minich DM, Brown BI: A Review of Dietary (Phyto)Nutrients for Glutathione Support. Nutrients. 2019 Sep 3;11(9):2073. doi: 10.3390/nu11092073. PMID: 31484368; PMCID: PMC6770193.
² Wu Guoyao et all: Glutathione metabolism and its implications for health. J Nutr. 2004 Mar;134(3):489-92. doi: 10.1093/jn/134.3.489. PMID: 14988435.